Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1975 Apr;64(4):535-98.

Potential value of plants as sources of new antifertility agents I

N R Farnsworth, A S Bingel, G A Cordell, F A Crane, H H Fong
  • PMID: 167146
Review

Potential value of plants as sources of new antifertility agents I

N R Farnsworth et al. J Pharm Sci. 1975 Apr.

Abstract

PIP: A comprehensive review of plants that possess contraceptive or interceptive, abortifacient, ecbolic, oxytocic, or emmenagogue properties is presented. The plants reviewed are those which have a folkloric reputation of contraceptive effects and those which have been tested on laboratory animals for their antifertility effect. The preovulatory, preimplantation, and postimplantation antifertility mechanisms of plant substances affecting the hypothalamus-pituitary, ovary, oviduct, uterus, or vagina are discussed in terms of reproductive differences among laboratory animal species. Lithospermic acid, m-Xylohydroquinone, coronaridine, rutin, and rottlerin are among the few active antifertility principles to be identified in higher plants. Volatile oils, quinine and castor oil, and sparteine have been used as abortifacient agents, but not with consistent success, and often with toxic, if not fetal, side effects.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

MeSH terms

LinkOut - more resources