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Case Reports
. 1991 Feb 23;337(8739):457-8.
doi: 10.1016/0140-6736(91)93395-p.

High-dose intravenous IgG treatment and renal function

J Schifferli  1 , M Leski, H Favre, P Imbach, U Nydegger, K Davies
Affiliations
Case Reports

High-dose intravenous IgG treatment and renal function

J Schifferli et al. Lancet. .

Abstract

In an open trial of high dose intravenous IgG (IVIG) treatment in nephrotic patients with glomerulonephritis, the first six patients so far studied showed a transient rise in plasma creatinine. This increase was not associated with any symptoms and the urinary deposit remained unchanged. Two other patients with pre-existing renal impairment but without nephrotic syndrome had a transient and reversible rise in plasma creatinine immediately after IVIG. These observations suggest that high-dose IVIG infusion can produce short-lived disturbances in renal function in patients with kidney diseases.

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  • Intravenous IgG for glomerulonephritis and renal function.
    Rostoker G, Philippon C, Belghiti D, Ben Maadi A, Remy P, Lang P, Lagrue G, Ozanne P, Bremard-Oury C, Weil B. Rostoker G, et al. Lancet. 1991 Jul 6;338(8758):54-5. doi: 10.1016/0140-6736(91)90043-o. Lancet. 1991. PMID: 1676105 No abstract available.

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