Comment on

• Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids.

  Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Araç D, et al. Nat Struct Mol Biol. 2006 Mar;13(3):209-17. doi: 10.1038/nsmb1056. Epub 2006 Feb 19. Nat Struct Mol Biol. 2006. PMID: 16491093
• Ca(2+)-synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion.

  Bhalla A, Chicka MC, Tucker WC, Chapman ER. Bhalla A, et al. Nat Struct Mol Biol. 2006 Apr;13(4):323-30. doi: 10.1038/nsmb1076. Epub 2006 Mar 26. Nat Struct Mol Biol. 2006. PMID: 16565726