Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Mar;11(3):1745-50.
doi: 10.1128/mcb.11.3.1745-1750.1991.

Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene

D H Yu  1 , K Scorsone, M C Hung
Affiliations

Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene

D H Yu et al. Mol Cell Biol. 1991 Mar.

Abstract

The adenovirus type 5 early region 1A (E1A) gene was introduced into neu-transformed B104-1-1 cells. Cells that expressed E1A possessed reduced transforming activity in vitro and reduced tumorigenicity in nude mice. These results demonstrate that the E1A gene products can act negatively to suppress the transformed phenotype in neu-transformed cells.

PubMed Disclaimer

References

    1. Oncogene. 1989 Aug;4(8):985-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1989 Apr;86(8):2545-8 - PubMed
    1. N Engl J Med. 1988 Nov 10;319(19):1239-45 - PubMed
    1. Science. 1987 Jan 9;235(4785):177-82 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Aug;85(15):5394-8 - PubMed

Publication types