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. 1991 Mar 9;337(8741):582-3.
doi: 10.1016/0140-6736(91)91641-7.

Cortisol response to corticotropin and survival in septic shock

P M Rothwell  1 , Z F Udwadia, P G Lawler
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Free article

Cortisol response to corticotropin and survival in septic shock

P M Rothwell et al. Lancet. .
Free article

Abstract

Corticotropin stimulation tests were used to assess adrenocortical function in 32 patients with septic shock. 13 patients had a poor cortisol response (rise less than 250 nmol/l) to corticotropin, all of whom died. However, there were only 6 deaths among the 19 patients with adequate responses (p less than 0.001). These results suggest that some patients with septic shock may have relative adrenocortical insufficiency.

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