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Comparative Study
. 2006 Jun;50(6):2251-4.
doi: 10.1128/AAC.00123-06.

Fluoroquinolone-resistant urinary isolates of Escherichia coli from outpatients are frequently multidrug resistant: results from the North American Urinary Tract Infection Collaborative Alliance-Quinolone Resistance study

James A Karlowsky  1 , Daryl J Hoban, Melanie R Decorby, Nancy M Laing, George G Zhanel
Affiliations
Comparative Study

Fluoroquinolone-resistant urinary isolates of Escherichia coli from outpatients are frequently multidrug resistant: results from the North American Urinary Tract Infection Collaborative Alliance-Quinolone Resistance study

James A Karlowsky et al. Antimicrob Agents Chemother. 2006 Jun.

Abstract

Ciprofloxacin-resistant Escherichia coli isolates (n = 1,858) from outpatient midstream urine specimens at 40 North American clinical laboratories in 2004 to 2005 were frequently resistant to ampicillin (79.8% of isolates) and trimethoprim-sulfamethoxazole (66.5%); concurrent resistance to cefdinir (9.0%) or nitrofurantoin (4.0%) was less common. Only 10.8% of isolates were resistant to ciprofloxacin alone. Fluoroquinolone-resistant isolates of E. coli from urine were frequently multidrug resistant.

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References

    1. Bolon, M. K., S. B. Wright, H. S. Gold, and Y. Carmeli. 2004. The magnitude of the association between fluoroquinolone use and quinolone-resistant Escherichia coli and Klebsiella pneumoniae may be lower than previously reported. Antimicrob. Agents Chemother. 48:1934-1940. - PMC - PubMed
    1. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing, vol. 25, no. 1. Fifteenth informational supplement M100-S15. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. Diekema, D. J., B. J. BootsMiller, T. E. Vaugh, R. F. Woolson, J. W. Yankey, E. J. Ernst, S. D. Flach, M. M. Ward, C. L. J. Franciscus, M. A. Pfaller, and B. N. Doebbeling. 2004. Antimicrobial resistance trends and outbreak frequency in United States hospitals. Clin. Infect. Dis. 38:78-85. - PubMed
    1. Eom, J.-S., B.-Y. Hwang, J.-W. Sohn, W.-J. Kim, M.-J. Kim, S.-C. Park, and H.-J. Cheong. 2002. Clinical and molecular epidemiology of quinolone-resistant Escherichia coli isolated from urinary tract infection. Microb. Drug Resist. 8:227-234. - PubMed
    1. Gupta, K., T. M. Hooton, and W. E. Stamm. 2001. Increasing antimicrobial resistance and the management of uncomplicated community-acquired urinary tract infections. Ann. Intern. Med. 135:41-50. - PubMed

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