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Comment
. 2006 Jun;168(6):1775-8.
doi: 10.2353/ajpath.2006.060270.

Translating mighty mice into neuromuscular therapeutics: is bigger muscle better?

Eric P Hoffman  1 , Diana Escolar
Affiliations
Comment

Translating mighty mice into neuromuscular therapeutics: is bigger muscle better?

Eric P Hoffman et al. Am J Pathol. 2006 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Relatively poor correlation of arm muscle size and strength in young adult males. Shown is data from a study of 1000 university students using volumetric magnetic resonance imaging and isometric strengths measurements (see Ref. for primary data).
See this image and copyright information in PMC

Comment on

References

    1. Parsons SA, Millay DP, Sargent MA, Mitchell R, McNally EM, Crandall DL, Molkentin JD. Age-dependent effect of myostatin blockage on disease severity in a murine model of limb-girdle muscular dystrophy. Am J Pathol. 2006;168:1975–1985. - PMC - PubMed
    1. Trappe SW, Trappe TA, Lee GA, Costill DL. Calf muscle strength in humans. Int J Sports Med. 2001;22:186–191. - PubMed
    1. Masuda K, Kikuhara N, Takahashi H, Yamanaka K. The relationship between muscle cross-sectional area and strength in various iso-kinetic movements among soccer players. J Sports Sci. 2003;21:851–858. - PubMed
    1. Hubal MJ, Gordish-Dressman H, Thompson PD, Price TB, Hoffman EP, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Clarkson PM. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc. 2005;37:964–972. - PubMed
    1. Perusse L, Lortie G, Leblanc C, Tremblay A, Theriault G, Bouchard C. Genetic and environmental sources of variation in physical fitness. Ann Hum Biol. 1987;14:425–434. - PubMed