Do antidepressants cure or create abnormal brain states?
- PMID: 16724872
- PMCID: PMC1472553
- DOI: 10.1371/journal.pmed.0030240
Do antidepressants cure or create abnormal brain states?
Abstract
Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental illness.
Conflict of interest statement
Figures
References
-
- Moncrieff J, Cohen D. Rethinking models of psychotropic drug action. Psychother Psychosom. 2005;74:145–153. - PubMed
-
- Hyman SE, Nestler EJ. Initiation and adaptation: A paradigm for understanding psychotropic drug action. Am J Psychiatry. 1996;153:151–162. - PubMed
-
- Schildkraut JJ. The catecholamine hypothesis of affective disorders: A review of supporting evidence. Am J Psychiatry. 1965;122:509–522. - PubMed
-
- Sargent PA, Kjaer KH, Bench CJ, Rabiner EA, Messa C, et al. Brain serotonin 1A receptor binding measured by positron emission tomography with [11C]WAY-100635: Effects of depression and antidepressant treatment. Arch Gen Psychiatry. 2000;57:174–180. - PubMed
-
- Drevets WC, Frank E, Price JC, Kupfer DJ, Holt D, et al. PET imaging of serotonin 1A receptor binding in depression. Biol Psychiatry. 1999;46:1375–1387. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical