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Review
. 2006 Jun;81(6):2328-34.
doi: 10.1016/j.athoracsur.2005.11.067.

Clinical value of the WHO classification system of thymoma

Frank C Detterbeck  1
Affiliations
Review

Clinical value of the WHO classification system of thymoma

Frank C Detterbeck. Ann Thorac Surg. 2006 Jun.

Abstract

Since the World Health Organization (WHO) histologic classification system for thymoma was introduced in 1999, several centers have published results using this system. This review of the published experience with the WHO system examines whether the classification is reproducible, whether the WHO system defines clinically distinct patient groups, assesses the independent prognostic value of the WHO type by multivariate analysis, and discusses the impact of the WHO system on clinical management decisions.

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