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Comment
. 2006;5(4):8.
doi: 10.1186/jbiol41. Epub 2006 May 25.

Regulators of kinesin involved in polarized trafficking and axon outgrowth

Shuo Luo  1 , Michael L Nonet
Affiliations
Comment

Regulators of kinesin involved in polarized trafficking and axon outgrowth

Shuo Luo et al. J Biol. 2006.

Abstract

Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.

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Figures

Figure 1
Figure 1
Schematic diagram of a kinesin-cargo complex. The cargo vesicles are thought to be associated with kinesins through the interactions between cargo-associated proteins (green) and adaptor proteins (yellow) as well as those between adaptors and kinesins (red). The heads of kinesin motors, which contact the microtubule, hydrolyze ATP and perform microtubule walking.
See this image and copyright information in PMC

Comment on

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