Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jun 7;12(21):3380-5.
doi: 10.3748/wjg.v12.i21.3385.

Malnutrition affects quality of life in gastroenterology patients

Affiliations

Malnutrition affects quality of life in gastroenterology patients

Kristina Norman et al. World J Gastroenterol. .

Abstract

Aim: To investigate the association between malnutrition and quality of life in patients with benign gastrointestinal disease.

Methods: Two hundred patients (104 wellnourished and 96 malnourished) were assessed according to the Subjective Global Assessment, anthropometric measurements and bioelectrical impedance analysis. Quality of life was determined with the validated Medical Outcomes Study 36-item Short-Form General Health Survey (SF 36). Muscle function was assessed by hand grip strength and peak flow.

Results: Body mass index, body cell mass, arm muscle area and hand grip strength were significantly lower in the malnourished patients. Quality of life was generally lower when compared to norm values. Seven out of eight quality of life scales (excluding bodily pain) were significantly reduced in the malnourished patients. Comparing patients with liver cirrhosis and inflammatory bowel disease (IBD), patients with IBD experienced significantly lower values in the perception of bodily pain,social functioning and mental health. Malnourished liver cirrhotics suffered reductions in more scales (six out of eight) than malnourished IBD patients did (four out of eight).

Conclusion: Quality of life is generally low in benign gastrointestinal disease and is further reduced in patients who are classified as malnourished. It appears that liver cirrhosis patients experience a higher quality of life than IBD patients do, but the impact of malnutrition seems to be greater in liver cirrhosis than in IBD.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Quality of life in the study population.
Figure 2
Figure 2
Quality of life (aP < 0.05, bP < 0.01).
Figure 3
Figure 3
Quality of life in malnourished vs well nourished patients (aP < 0.05, bP < 0.01).

References

    1. Norman K, Schütz T, Kemps M, Josef Lübke H, Lochs H, Pirlich M. The Subjective Global Assessment reliably identifies malnutrition-related muscle dysfunction. Clin Nutr. 2005;24:143–150. - PubMed
    1. Russell DM, Walker PM, Leiter LA, Sima AA, Tanner WK, Mickle DA, Whitwell J, Marliss EB, Jeejeebhoy KN. Metabolic and structural changes in skeletal muscle during hypocaloric dieting. Am J Clin Nutr. 1984;39:503–513. - PubMed
    1. Drewnowski A, Evans WJ. Nutrition, physical activity, and quality of life in older adults: summary. J Gerontol A Biol Sci Med Sci. 2001;56 Spec No 2:89–94. - PubMed
    1. Vetta F, Ronzoni S, Taglieri G, Bollea MR. The impact of malnutrition on the quality of life in the elderly. Clin Nutr. 1999;18:259–267. - PubMed
    1. Kobayashi K, Nomura K, Wakasawa S, Sudou Y, Takahashi T, Nukariya N, Hisakatsu S, Hayashihara K, Yoshimori K, Murata A. [Quality of life (QOL) and nutrition] Gan To Kagaku Ryoho. 1991;18:1031–1038. - PubMed

MeSH terms