Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Jun:38 Suppl:S2-7.
doi: 10.1038/ng1794.

Approaches to microRNA discovery

Eugene Berezikov  1 , Edwin Cuppen, Ronald H A Plasterk
Affiliations
Review

Approaches to microRNA discovery

Eugene Berezikov et al. Nat Genet. 2006 Jun.

Abstract

MicroRNAs (miRNAs) are noncoding RNAs that can regulate gene expression. Several hundred genes encoding miRNAs have been experimentally identified in animals, and many more are predicted by computational methods. How can new miRNAs be discovered and distinguished from other types of small RNA? Here we summarize current methods for identifying and validating miRNAs and discuss criteria used to define an miRNA.

PubMed Disclaimer

LinkOut - more resources