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. 1991 May 25;337(8752):1248-50.
doi: 10.1016/0140-6736(91)92919-s.

Schizophrenia after prenatal exposure to 1957 A2 influenza epidemic

E O'Callaghan  1 , P Sham, N Takei, G Glover, R M Murray
Affiliations

Schizophrenia after prenatal exposure to 1957 A2 influenza epidemic

E O'Callaghan et al. Lancet. .

Abstract

The birth dates of schizophrenic inpatients in eight health regions in England and Wales were reviewed for any effect of the 1957 A2 influenza epidemic. 5 months after the peak infection prevalence, the number of births of individuals who later developed schizophrenia was 88% higher than the average number of such births in the corresponding periods of the 2 previous and the next 2 years. This finding is in accordance with a study from Helsinki and with clinical and neuropathological evidence of aberrant fetal brain development in the pathogenesis of schizophrenia.

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  • Schizophrenia and influenza.
    [No authors listed] [No authors listed] Lancet. 1991 Jul 13;338(8759):116-9. Lancet. 1991. PMID: 1676443 No abstract available.

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