Acceleration of gluconeogenesis from lactate by lysine (Short Communication)
- PMID: 16742833
- PMCID: PMC1177859
- DOI: 10.1042/bj1340671
Acceleration of gluconeogenesis from lactate by lysine (Short Communication)
Abstract
l-Lysine (2mm) causes an increase (mean 60%) in the rate of gluconeogenesis from lactate in isolated liver cells. The effect is of a catalytic nature. No other amino acid has the same effect, though ornithine is slightly active. The effect is additional to the stimulatory effects of oleate and of dibutyryl cyclic AMP.
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