Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Apr;9(4):623-8.
doi: 10.1016/0888-7543(91)90355-i.

Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2

J M Vance  1 , D Barker, L H Yamaoka, J M Stajich, L Loprest, W Y Hung, K Fischbeck, A D Roses, M A Pericak-Vance
Affiliations

Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2

J M Vance et al. Genomics. 1991 Apr.

Abstract

Charcot-Marie-Tooth (CMT) disease type 1a has been previously localized to chromosome 17 using the markers D17S58 and D17S71. In that report we were unable to provide unequivocal localization of the CMT1A gene on either the proximal p or the q arm. Therefore, data from one additional CMT1A family and typing of other probes spanning the pericentromeric region of chromosome 17 (D17S73, D17S58, D17S122, D17S125, D17S124) were analyzed. Multipoint analysis demonstrates convincing evidence (log likelihood difference greater than 5) that the CMT1A gene lies within 17p11.2 and most likely between the flanking markers D17S122 and D17S124.

PubMed Disclaimer

Publication types

LinkOut - more resources