Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Jun 2;125(5):827-9.
doi: 10.1016/j.cell.2006.05.018.

Rethinking the microprocessor

Hervé Seitz  1 , Phillip D Zamore
Affiliations
Free article
Review

Rethinking the microprocessor

Hervé Seitz et al. Cell. .
Free article

Abstract

MicroRNAs (miRNAs) are tiny regulators of gene expression that are processed from longer primary transcripts. In this issue, Han et al. (2006) report some of the structural features of the primary transcript that ensure that the Drosha-DGCR8 enzyme complex liberates precisely the correct precursor sequence, enabling production of a fully functional miRNA.

PubMed Disclaimer

Comment on

LinkOut - more resources