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. 2006 Jun;72(6):4446-9.
doi: 10.1128/AEM.01924-05.

Inactivation of Mycobacterium avium subsp. paratuberculosis in cow's milk by means of high hydrostatic pressure at mild temperatures

Tomás López-Pedemonte  1 , Iker Sevilla, Joseba M Garrido, Gorka Aduriz, Buenaventura Guamis, Ramón A Juste, Artur X Roig-Sagués
Affiliations

Inactivation of Mycobacterium avium subsp. paratuberculosis in cow's milk by means of high hydrostatic pressure at mild temperatures

Tomás López-Pedemonte et al. Appl Environ Microbiol. 2006 Jun.

Abstract

Two strains of Mycobacterium avium subsp. paratuberculosis (3644/02 and ATCC 19698) were inoculated (approximately 6 log CFU/ml) into sterilized milk to evaluate inactivation by high hydrostatic pressure. Reductions of M. avium subsp. paratuberculosis increased with pressure level. Significant differences were also found between M. avium subsp. paratuberculosis strains and between the media used. Average reductions of 4 log CFU/ml after treatment with 500 MPa are comparable to those caused by thermal treatments.

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