Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2006 Jul;3(7):e292.
doi: 10.1371/journal.pmed.0030292.

Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1

Affiliations
Comparative Study

Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1

Michael Levin. PLoS Med. 2006 Jul.

Abstract

Levin discusses a new study, by Meager and colleagues, which identified a novel target of the disordered immune response in patients with APS-1.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The author declares that he has no competing interests.

Comment on

Similar articles

Cited by

  • Anti-cytokine autoantibodies: mechanistic insights and disease associations.
    Cheng A, Holland SM. Cheng A, et al. Nat Rev Immunol. 2024 Mar;24(3):161-177. doi: 10.1038/s41577-023-00933-2. Epub 2023 Sep 19. Nat Rev Immunol. 2024. PMID: 37726402 Review.
  • Autoantibodies to Interferons in Infectious Diseases.
    Quiros-Roldan E, Sottini A, Signorini SG, Serana F, Tiecco G, Imberti L. Quiros-Roldan E, et al. Viruses. 2023 May 22;15(5):1215. doi: 10.3390/v15051215. Viruses. 2023. PMID: 37243300 Free PMC article. Review.
  • Exome Sequencing Reveals Mutations in AIRE as a Cause of Isolated Hypoparathyroidism.
    Li D, Streeten EA, Chan A, Lwin W, Tian L, Pellegrino da Silva R, Kim CE, Anderson MS, Hakonarson H, Levine MA. Li D, et al. J Clin Endocrinol Metab. 2017 May 1;102(5):1726-1733. doi: 10.1210/jc.2016-3836. J Clin Endocrinol Metab. 2017. PMID: 28323927 Free PMC article.
  • Monogenic autoimmune diseases: insights into self-tolerance.
    Su MA, Anderson MS. Su MA, et al. Pediatr Res. 2009 May;65(5 Pt 2):20R-25R. doi: 10.1203/PDR.0b013e31819dc55c. Pediatr Res. 2009. PMID: 19190526 Free PMC article. Review.
  • Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.
    Le Voyer T, Parent AV, Liu X, Cederholm A, Gervais A, Rosain J, Nguyen T, Perez Lorenzo M, Rackaityte E, Rinchai D, Zhang P, Bizien L, Hancioglu G, Ghillani-Dalbin P, Charuel JL, Philippot Q, Gueye MS, Maglorius Renkilaraj MRL, Ogishi M, Soudée C, Migaud M, Rozenberg F, Momenilandi M, Riller Q, Imberti L, Delmonte OM, Müller G, Keller B, Orrego J, Franco Gallego WA, Rubin T, Emiroglu M, Parvaneh N, Eriksson D, Aranda-Guillen M, Berrios DI, Vong L, Katelaris CH, Mustillo P, Raedler J, Bohlen J, Bengi Celik J, Astudillo C, Winter S; NF-κB Consortium; COVID Human Genetic Effort; McLean C, Guffroy A, DeRisi JL, Yu D, Miller C, Feng Y, Guichard A, Béziat V, Bustamante J, Pan-Hammarström Q, Zhang Y, Rosen LB, Holland SM, Bosticardo M, Kenney H, Castagnoli R, Slade CA, Boztuğ K, Mahlaoui N, Latour S, Abraham RS, Lougaris V, Hauck F, Sediva A, Atschekzei F, Sogkas G, Poli MC, Slatter MA, Palterer B, Keller MD, Pinzon-Charry A, Sullivan A, Droney L, Suan D, Wong M, Kane A, Hu H, Ma C, Grombiříková H, Ciznar P, Dalal I, Aladjidi N, Hie M, Lazaro E, Franco J, Keles S, Malphettes M, Pasquet M, Maccari ME, Meinhardt A, Ikinciogullari A, Shahrooei M, Celmeli F, Frosk P, Goodnow CC, Gray PE, Bel… See abstract for full author list ➔ Le Voyer T, et al. Nature. 2023 Nov;623(7988):803-813. doi: 10.1038/s41586-023-06717-x. Epub 2023 Nov 8. Nature. 2023. PMID: 37938781 Free PMC article.

References

    1. Eisenbarth GS, Gottlieb PA. Autoimmune polyendocrine syndromes. N Eng J Med. 2004;350:2068–2079. - PubMed
    1. Morahan G, Morel L. Genetics of autoimmune diseases in humans and in animal models. Curr Opin Immunol. 2002;14:803–811. - PubMed
    1. Betterle C, Greggio NA, Volpato M. Autoimmune polyglandular syndrome type 1. J Clin Endocrinol Metab. 1998;83:1049–55. - PubMed
    1. Ahonen P, Myllarniemi S, Sipila I, Perheentupa J. Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Eng J Med. 1990;322:1829–1836. - PubMed
    1. Soderbergh A, Myhre AG, Ekwall O, Gebre-Medhin G, Hedstrand H, et al. Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. J Clin Endocrinol Metab. 2004;89:557–562. - PubMed

MeSH terms