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Case Reports
. 2006 Jul;91(7):1001.
Epub 2006 Jun 1.

Life-threatening motor neurotoxicity in association with bortezomib

Sunil Gupta, Antonio Pagliuca, Steve Devereux, Ghulam J Mufti, Steve Schey
  • PMID: 16757419
Case Reports

Life-threatening motor neurotoxicity in association with bortezomib

Sunil Gupta et al. Haematologica. 2006 Jul.

Abstract

Bortezomib has been licensed to be used in relapsed and refractory multiple myeloma. It is a promising agent for this incurable condition but our effort is to caution hematologists about the life-threatening neurotoxicity (grade 4) which was seen in two of six patients treated with this agent although the complication cannot definitely be attributed to bortezomib.

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