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Review
. 2006 Jun;114(6):936-42.
doi: 10.1289/ehp.8527.

Biomonitoring of exposure in farmworker studies

Dana B Barr  1 , Kent Thomas, Brian Curwin, Doug Landsittel, James Raymer, Chensheng Lu, K C Donnelly, John Acquavella
Affiliations
Review

Biomonitoring of exposure in farmworker studies

Dana B Barr et al. Environ Health Perspect. 2006 Jun.

Abstract

Although biomonitoring has been used in many occupational and environmental health and exposure studies, we are only beginning to understand the complexities and uncertainties involved with the biomonitoring process--from study design, to sample collection, to chemical analysis--and with interpreting the resulting data. We present an overview of concepts that should be considered when using biomonitoring or biomonitoring data, assess the current status of biomonitoring, and detail potential advancements in the field that may improve our ability to both collect and interpret biomonitoring data. We discuss issues such as the appropriateness of biomonitoring for a given study, the sampling time frame, temporal variability in biological measurements to nonpersistent chemicals, and the complex issues surrounding data interpretation. In addition, we provide recommendations to improve the utility of biomonitoring in farmworker studies.

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Figures

Figure 1
Figure 1
Hypothetical postexposure fate of an NPP after a single exposure, represented by the y-axis. Adapted from Needham and Sexton (2000).
Figure 2
Figure 2
Hypothetical postexposure fate of an NPP in blood and urine after repeated (chronic) exposures.
Figure 3
Figure 3
Pathway for biological measurements.
See this image and copyright information in PMC

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