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Review
. 2006 Jul;45(Pt 1):1-12.
doi: 10.1042/BA20050233.

Bioreactor systems for the production of biopharmaceuticals from animal cells

James N Warnock  1 , Mohamed Al-Rubeai
Affiliations
Review

Bioreactor systems for the production of biopharmaceuticals from animal cells

James N Warnock et al. Biotechnol Appl Biochem. 2006 Jul.

Abstract

The demand for biopharmaceutical products is set to see a significant increase over the next few years. As a consequence, the processes used to produce these products must be able to meet market requirements. The present paper reviews the current technologies available for animal cell culture and highlights the advantages and disadvantages of each method, while also providing details of recent case studies. Processes are described for both suspension and anchorage-dependent cell lines.

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