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. 2006 Jul;55(7):912-4.
doi: 10.1136/gut.2005.085902.

Hedgehog Wnteraction in colorectal cancer

G R van den Brink  1 , J C H Hardwick
Affiliations

Hedgehog Wnteraction in colorectal cancer

G R van den Brink et al. Gut. 2006 Jul.

Abstract

The Hedgehog pathway was recently shown to antagonise constitutive activity of the Wnt pathway that drives proliferation of colorectal cancer cells. Studies in this issue of Gut refine our understanding of the underlying mechanism and provide evidence for such antagonism in colorectal cancers in vivo

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Conflict of interest statement

Conflict of interest: None declared.

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