Cellular immune responses against persistent hepatitis C virus: gone but not forgotten
- PMID: 16766748
- PMCID: PMC1856310
- DOI: 10.1136/gut.2005.087304
Cellular immune responses against persistent hepatitis C virus: gone but not forgotten
Abstract
Failure to sustain antiviral T cell responses is a hallmark of persistent hepatitis C virus infection. Early loss of T cell proliferative capacity after acute disease appears to be an important component of this process. T cell function may, however, be restored in vitro with interleukin 2
Comment on
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Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance.Gut. 2006 Jul;55(7):1012-9. doi: 10.1136/gut.2005.080077. Epub 2006 Feb 16. Gut. 2006. PMID: 16484505 Free PMC article.
References
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- Bowen D G, Walker C M. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005436946–952. - PubMed
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