Calcium signals control Wnt-dependent dendrite growth
- PMID: 16772162
- DOI: 10.1016/j.neuron.2006.06.001
Calcium signals control Wnt-dependent dendrite growth
Abstract
Activity-dependent dendritic growth is dependent upon intracellular calcium signaling. Yet the specific mechanisms by which calcium signals lead to morphologic changes in dendrites are not well understood. A paper in this issue of Neuron by Wayman et al. describes a novel calcium-dependent signaling cascade linking neuronal activity and calcium influx to expression of Wnt-2, a member of a family of proteins that controls elaboration of dendrites.
Comment on
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Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2.Neuron. 2006 Jun 15;50(6):897-909. doi: 10.1016/j.neuron.2006.05.008. Neuron. 2006. PMID: 16772171
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