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Case Reports
. 2006 May;28(5):286-9.
doi: 10.1097/01.mph.0000212901.84146.5a.

Treatment of stage IV malignant rhabdoid tumor of the kidney (MRTK) with ICE and VDCy: a case report

Masaki Yamamoto  1 , Nobuhiro Suzuki, Naoki Hatakeyama, Nobuo Mizue, Tsukasa Hori, Yuki Kuroiwa, Masato Hareyama, Takanori Oda, Tooru Kudoh, Akihiro Nui, Takashi Matsuno, Toshinori Hirama, Shigeaki Yokoyama, Jeffrey S Dome, Hiroyuki Tsutsumi
Affiliations
Case Reports

Treatment of stage IV malignant rhabdoid tumor of the kidney (MRTK) with ICE and VDCy: a case report

Masaki Yamamoto et al. J Pediatr Hematol Oncol. 2006 May.

Abstract

The prognosis of stage IV malignant rhabdoid tumor of the kidney (MRTK) has been extremely poor. However, a combination of ICE (ifosfamide, carboplatin, and etoposide) and VDCy (vincristine, doxorubicin, and cyclophosphamide) was recently reported to be effective for metastatic MRTK. We describe a 21-month-old girl with stage IV MRTK who was successfully treated with ICE, VDCy, and radiotherapy. She remained well, without recurrence, 24 months after diagnosis. Alternating therapy with ICE and VDCy might become a standard regimen for stage IV MRTK, although further study is required to confirm its effectiveness.

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