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Randomized Controlled Trial
. 2006 Oct;77(10):913-8.
doi: 10.1007/s00104-006-1202-7.

[Analgesia in colon surgery. Can the use of NSAIDs reduce the opioid consumption following conventional and laparoscopic interventions?]

[Article in German]
B Kraft  1 , S Leroy, M Schweizer, W Junginger, R Bittner
Affiliations
Randomized Controlled Trial

[Analgesia in colon surgery. Can the use of NSAIDs reduce the opioid consumption following conventional and laparoscopic interventions?]

[Article in German]
B Kraft et al. Chirurg. 2006 Oct.

Abstract

Background: The goal of our study was to evaluate the morphine-sparing effect of nonsteroidal anti-inflammatory drugs (NSAIDs) following both conventional and laparoscopic colon surgery.

Materials and methods: In this prospective, randomized clinical trial, 180 patients were assigned to three groups. Two groups received either paracetamol or parecoxib/valdecoxib in addition to piritramid via patient-controlled or nurse-controlled analgesia pump. Patients in the control group received piritramid only. The total piritramid consumption during hospital stay was recorded.

Results: Total opioid consumption was significantly lower in the two groups who received NSAIDs. Comparing conventional and laparoscopic surgery, the latter group had much lower opioid consumption.

Conclusion: The use of NSAIDs following colon surgery significantly reduces postoperative opioid consumption.

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References

    1. Anaesthesist. 2004 Dec;53(12):1211-8 - PubMed
    1. Anesthesiology. 2006 Mar;104(3):518-26 - PubMed
    1. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2002 Sep;45(9):699-706 - PubMed
    1. Lancet. 2003 Mar 15;361(9361):968-9 - PubMed
    1. AANA J. 2006 Feb;74(1):49-60 - PubMed

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