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Review
. 2006 Jun;20(3):593-9.
doi: 10.1016/j.berh.2006.03.002.

Genetics of spondyloarthritis

Maxime Breban  1
Affiliations
Review

Genetics of spondyloarthritis

Maxime Breban. Best Pract Res Clin Rheumatol. 2006 Jun.

Abstract

This chapter reviews evidence from family and twin studies supporting the strong genetic predisposition of the spondyloarthritides (SpA), which is only partially attributable to the major histocompatibility locus. The current concept of SpA heterogeneity has been challenged by family studies which showed that all articular and extra-articular manifestations were linked together, and most likely to the same genetic factors.

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