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Comment
. 2006 Jun 16;125(6):1032-4.
doi: 10.1016/j.cell.2006.06.002.

Exploring transcriptional regulatory networks in the worm

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Exploring transcriptional regulatory networks in the worm

Illés J Farkas et al. Cell. .
Free article

Abstract

Using a yeast one-hybrid assay, Deplancke et al. (2006) report in this issue a protein-DNA interaction network for 72 gene promoters and 117 regulatory proteins expressed in cells of the nematode digestive tract. This study is a first step toward mapping transcriptional regulatory networks in distinct metazoan cell lineages and organs using a "gene-centered" approach.

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  • A gene-centered C. elegans protein-DNA interaction network.
    Deplancke B, Mukhopadhyay A, Ao W, Elewa AM, Grove CA, Martinez NJ, Sequerra R, Doucette-Stamm L, Reece-Hoyes JS, Hope IA, Tissenbaum HA, Mango SE, Walhout AJ. Deplancke B, et al. Cell. 2006 Jun 16;125(6):1193-205. doi: 10.1016/j.cell.2006.04.038. Cell. 2006. PMID: 16777607

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