Exploring transcriptional regulatory networks in the worm
- PMID: 16777593
- DOI: 10.1016/j.cell.2006.06.002
Exploring transcriptional regulatory networks in the worm
Abstract
Using a yeast one-hybrid assay, Deplancke et al. (2006) report in this issue a protein-DNA interaction network for 72 gene promoters and 117 regulatory proteins expressed in cells of the nematode digestive tract. This study is a first step toward mapping transcriptional regulatory networks in distinct metazoan cell lineages and organs using a "gene-centered" approach.
Comment on
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A gene-centered C. elegans protein-DNA interaction network.Cell. 2006 Jun 16;125(6):1193-205. doi: 10.1016/j.cell.2006.04.038. Cell. 2006. PMID: 16777607
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