Comment
doi: 10.1016/j.cell.2006.06.003.
P-bodies react to stress and nonsense
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- PMID: 16777595
- DOI: 10.1016/j.cell.2006.06.003
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Comment
P-bodies react to stress and nonsense
Cell.
.
Free article
Abstract
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
Comment on
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Targeting of aberrant mRNAs to cytoplasmic processing bodies.Cell. 2006 Jun 16;125(6):1095-109. doi: 10.1016/j.cell.2006.04.037. Cell. 2006. PMID: 16777600 Free PMC article.
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Relief of microRNA-mediated translational repression in human cells subjected to stress.Cell. 2006 Jun 16;125(6):1111-24. doi: 10.1016/j.cell.2006.04.031. Cell. 2006. PMID: 16777601
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