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Comparative Study
. 2005:2005:864-8.

Alignment of multiple ontologies of anatomy: deriving indirect mappings from direct mappings to a reference

Songmao Zhang  1 , Olivier Bodenreider
Affiliations
Comparative Study

Alignment of multiple ontologies of anatomy: deriving indirect mappings from direct mappings to a reference

Songmao Zhang et al. AMIA Annu Symp Proc. 2005.

Abstract

Objective: To investigate the indirect alignment of two anatomical ontologies through a reference ontology and to compare it to direct alignment between these two ontologies. The ontologies under investigation are the Adult Mouse Anatomical Dictionary (MA) and the NCI Thesaurus (NCI). The Foundational Model of Anatomy serves as reference ontology.

Methods: The direct alignment employs a combination of lexical and structural similarity. The indirect alignment simply derives mappings from direct alignments to the reference ontology.

Results: The indirect MA-NCI alignment yielded 703 mappings and the direct alignment 715, 654 of which are common to both. The mappings specific to one approach were analyzed.

Conclusions: When a reference ontology exists, indirect alignment of multiple ontologies through a reference represents a valid, cost-effective alternative to pairwise alignment.

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Figures

Figure 1
Figure 1
Aligning multiple ontologies
Figure 2
Figure 2
Direct vs. indirect alignment
Figure 3a
Figure 3a
Indirect MA-NCI alignment through FMA
Figure 3b
Figure 3b
Direct vs. indirect alignment
See this image and copyright information in PMC

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