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. 1991 Jun;29(6):1194-201.
doi: 10.1128/jcm.29.6.1194-1201.1991.

Repeated DNA in Pneumocystis carinii

S L Stringer  1 , S T Hong, D Giuntoli, J R Stringer
Affiliations

Repeated DNA in Pneumocystis carinii

S L Stringer et al. J Clin Microbiol. 1991 Jun.

Abstract

A 16-kb DNA fragment designated Rp3-1 and cloned from the genome of rat-derived Pneumocystis carinii was found to contain sequences that were repeated approximately 70 times per genome. The repeated sequences in Rp3-1 spanned at least 10.4 kb. Sequences in Rp3-1 were present on each of the 16 P. carinii chromosomes resolved by field inversion gel electrophoresis. Most of the P. carinii genomic sequences homologous to those in the Rp3-1 clone appeared to be as long as those in the Rp3-1 clone but were highly polymorphic with respect to restriction enzyme cleavage sites. The Rp3-1 DNA fragment appears to be a member of a family of large, degenerate, dispersed repeats.

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References

    1. Proc Natl Acad Sci U S A. 1989 Sep;86(17):6503-7 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1974;38:475-82 - PubMed
    1. Mol Cell Biol. 1987 Nov;7(11):3937-46 - PubMed
    1. Mol Cell Biol. 1985 Oct;5(10):2613-22 - PubMed
    1. Nature. 1988 Aug 11;334(6182):519-22 - PubMed

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