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Review
. 2006 Jun;24(6):667-669.
doi: 10.1016/j.immuni.2006.06.007.

Outside influence: TLRs direct hematopoietic cell fates

T Matt Holl  1 , Garnett Kelsoe  2
Affiliations
Free article
Review

Outside influence: TLRs direct hematopoietic cell fates

T Matt Holl et al. Immunity. 2006 Jun.
Free article

Abstract

Toll-like receptors (TLRs) modulate immune responses indirectly by promoting the efficacy of antigen presentation. In this issue of Immunity, Nagai et al. (2006) demonstrate that TLR signals also bias hematopoietic progenitor cells toward myelopoiesis directly by replacing cytokine and differentiative cues.

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