Review
doi: 10.1016/j.immuni.2006.06.005.
AID for innate immunity to retroviral transformation
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- PMID: 16782023
- DOI: 10.1016/j.immuni.2006.06.005
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Review
AID for innate immunity to retroviral transformation
Immunity.
2006 Jun.
Free article
Abstract
AID is a cytidine deaminase essential for class switch recombination and somatic hypermutation during the humoral immune response. In this issue of Immunity, Gourzi et al. (2006) show that AID also plays a critical role in innate immunity to virally induced acute pro-B cell leukemia.
Comment on
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A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.Immunity. 2006 Jun;24(6):779-786. doi: 10.1016/j.immuni.2006.03.021. Immunity. 2006. PMID: 16782033
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