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Review
. 2006 Jun 17;367(9527):2010-8.
doi: 10.1016/S0140-6736(06)68891-0.

Osteoporosis

Philip Sambrook  1 , Cyrus Cooper
Affiliations
Review

Osteoporosis

Philip Sambrook et al. Lancet. .

Erratum in

  • Lancet. 2006 Jul 1;368(9529):28

Abstract

Osteoporosis is a serious public health issue. The past 10 years have seen great advances in our understanding of its epidemiology, pathophysiology, and treatment, and further advances are rapidly being made. Clinical assessment will probably evolve from decisions mainly being made on the basis of bone densitometry, to use of algorithms of absolute fracture risk. Biochemical markers of bone turnover are also likely to become more widely used. Bisphosphonates will probably remain the mainstay of therapy, but improved understanding of the optimum amount of remodelling suppression and duration of therapy will be important. At the same time, other diagnostic and therapeutic approaches, including biological agents, are likely to become more widespread.

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Comment in

  • Type 2 diabetes and fracture risk.
    Mascitelli L, Pezzetta F. Mascitelli L, et al. Lancet. 2006 Aug 26;368(9537):732. doi: 10.1016/S0140-6736(06)69281-7. Lancet. 2006. PMID: 16935682 No abstract available.

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