Morphology of BHK-21 Cells Infected with Sindbis Virus Temperature-Sensitive Mutants in Complementation Groups D and E
- PMID: 16789157
- PMCID: PMC354582
- DOI: 10.1128/JVI.15.5.1262-1266.1975
Morphology of BHK-21 Cells Infected with Sindbis Virus Temperature-Sensitive Mutants in Complementation Groups D and E
Abstract
BHK-21 cells infected with temperature-sensitive mutants of Sindbis virus in complementation groups D and E differed in their appearance under nonpermissive conditions. Cells infected at nonpermissive temperature with virus defective in complementation group E had nucleocapsids attached in large numbers to the inside surface of the host plasma membrane. Infection with a group D mutant produced nucleocapsids that did not attach to the plasma membrane but rather remained free in the cell cytoplasm.
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