Comparative Study
doi: 10.1016/0006-8993(75)90878-1.
Denervation in the primary olfactory pathway of mice. II. Effects on carnosine and other amine compounds
- PMID: 167914
- DOI: 10.1016/0006-8993(75)90878-1
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Comparative Study
Denervation in the primary olfactory pathway of mice. II. Effects on carnosine and other amine compounds
Brain Res.
.
Abstract
Carnosine (beta-alanyl-histidine) is present in the olfactory bulb and olfactory eqithelium of mice and rats at 1-2 nmole/mg tissue. Peripheral deafferentation or central denervation causes a rapid, selective decrease of this depeptide from the reciprocal portion of the primary olfactory pathway. These data demonstrate the localization of carnosine within the primary olfactory chemoreceptor neurons and suggest a possible role for this compound in neural transmission.
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