Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Jul;145(1):1-4.
doi: 10.1111/j.1365-2249.2006.03131.x.

The contribution of Bruce Glick to the definition of the role played by the bursa of Fabricius in the development of the B cell lineage

D Ribatti  1 , E Crivellato, A Vacca
Affiliations

The contribution of Bruce Glick to the definition of the role played by the bursa of Fabricius in the development of the B cell lineage

D Ribatti et al. Clin Exp Immunol. 2006 Jul.

Abstract

In 1956, Bruce Glick and Timothy Chang reported that the bursa of Fabricius plays an important role in antibody production. Their demonstration that antibody responses are suppressed in the majority of bursectomized chickens became the cornerstone of modern immunology. Bursa research increased considerably during the 1960s and early 1970s.

PubMed Disclaimer

References

    1. Smith SB, Macchi V, Parenti A, De Caro R. Hieronymus Fabricius ab Acquapendente (1533–1619) Clin Anat. 2004;17:540–3. - PubMed
    1. Adelman HB. The Embryological Treatise of Hieronymus Fabricius of Aquapendente. Vol. 1. Ithaca, New York: Cornell University Press; 1967. pp. 147–91.
    1. Hamilton HL. Lillie’s development of the chick. New York: Holt, Rinehart and Winston; 1952. pp. 390–1.
    1. Romanoff AL. The avian embryo. New York: Macmillan; 1960. pp. 497–508.
    1. Ackerman GA, Knouff RA. Lymphocytopoiesis in the bursa of Fabricius. Am J Anat. 1959;104:163–205. - PubMed

Publication types