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. 2006 Sep 1;16(17):4586-91.
doi: 10.1016/j.bmcl.2006.06.005. Epub 2006 Jun 21.

Two novel immunosuppressive pregnane glycosides from the roots of Stephanotis mucronata

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Two novel immunosuppressive pregnane glycosides from the roots of Stephanotis mucronata

Yiping Ye et al. Bioorg Med Chem Lett. .

Abstract

Two novel pregnane glycosides, together with one new aglycone, were isolated from the roots of Stephanotis mucronata. Their structures were determined by means of chemical evidence and extensive spectroscopic methods including 1D and 2D NMR. The two pregnane glycosides displayed significant immunosuppressive activities in vitro.

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