Is restricted randomisation necessary?
- PMID: 16793819
- PMCID: PMC1482349
- DOI: 10.1136/bmj.332.7556.1506
Is restricted randomisation necessary?
Abstract
Restrictions during randomisation make it easier for investigators to guess the next allocation. Statistical correction of any imbalance in confounders at the end of the study is equally accurate for most trials and would be safer
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References
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