Erythropoietin and blood doping
- PMID: 16799100
- PMCID: PMC2657498
- DOI: 10.1136/bjsm.2006.027532
Erythropoietin and blood doping
Abstract
Objective and method: To outline the direct and indirect approaches in the fight against blood doping in sports, the different strategies that have been used and are currently being used to fight efficiently against blood doping are presented and discussed.
Results and conclusions: The paper outlines the different approaches and diagnostic tools that some federations have to identify and target sports people demonstrating abnormal blood profiles. Originally blood tests were introduced for medical reasons and for limiting misuse of recombinant human erythropoietin (rHuEPO). In this way it became possible to prevent athletes with haematocrit levels well above normal, and potentially dangerous for their health, competing in sport. Today, with nearly a decade of blood testing experience, sports authorities should be familiar with some of the limitations and specially the ability of blood tests performed prior to competitions to fight efficiently against the misuse of rHuEPO, blood transfusion, and artificial haemoglobin.
Conflict of interest statement
Competing interests: none declared
References
-
- Koury M J, Sawyer S T, Brandt S J. New insights into erythropoiesis. Curr Opin Hematol 2002993–100. - PubMed
-
- Eckardt K U, Bauer C. Erythropoietin in health and disease. Eur J Clin Invest 198919117–127. - PubMed
-
- Fisher J W. Erythropoietin: physiology and pharmacology update. Exp Biol Med (Maywood) 20032281–14. - PubMed
-
- Fisher J W. A quest for erythropoietin over nine decades. Annu Rev Pharmacol Toxicol 1998381–20. - PubMed
-
- Lacombe C, Mayeux P. The molecular biology of erythropoietin. Nephrol Dial Transplant 199914(Suppl 2)22–28. - PubMed
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