[Plasmids controlling the resistance to several antibiotics in C. perfringens type A, strain 659]
[Article in
French]
- PMID: 167997
Item in Clipboard
[Plasmids controlling the resistance to several antibiotics in C. perfringens type A, strain 659]
[Article in
French]
C R Acad Hebd Seances Acad Sci D.
.
Abstract
A strain of C. perfringens type A, isolated from a patient, was found to be resistant to four antibiotics: tetracycline (Tet), chloramphénicol (Chl), erythromycin (Ero) and clindamycin (Cli). Clones resistant to only two drugs (Tet-Chl or Ero-Cli), or sensitive to all drugs were found in cultures of the wild-type strain treated by acridine dyes or ethidium bromide. DNA analysis by equilibrium centrifugation confirmed that the original strain contains two resistance plasmids, one called Rip 401 (Tet-Chl) and the other Rip 402 (Ero-Cli), which represent respectively 1.8 +/- 0.2% and 2.3 +/- 0.2% of the total amount of DNA in this strain of Cl. perfrigens.
Similar articles
-
[Transfer of the tetracycline-chloramphenicol plasmid in Clostridium perfringens].C R Acad Hebd Seances Acad Sci D. 1975 Jul 28;281(4):317-9. C R Acad Hebd Seances Acad Sci D. 1975. PMID: 172257 French.
-
[Transferable tetracycline resistance in "Clostridium difficile" (author's transl)].Ann Microbiol (Paris). 1980 Mar-Apr;131A(2):171-9. Ann Microbiol (Paris). 1980. PMID: 6247949 French.
-
Antibiotic susceptibility of Clostridium species isolated from human infections.Scand J Infect Dis. 1975;7(2):127-34. doi: 10.3109/inf.1975.7.issue-2.09. Scand J Infect Dis. 1975. PMID: 170668
-
Antibiotic resistance plasmids and mobile genetic elements of Clostridium perfringens.Plasmid. 2018 Sep;99:32-39. doi: 10.1016/j.plasmid.2018.07.002. Epub 2018 Jul 26. Plasmid. 2018. PMID: 30055188 Review.
-
Mechanism of antimicrobial resistance and resistance transfer in anaerobic bacteria.Scand J Infect Dis Suppl. 1982;35:37-44. Scand J Infect Dis Suppl. 1982. PMID: 6300995 Review.
Cited by
-
Changing patterns of plasmid-mediated drug resistance during tetracycline therapy.Antimicrob Agents Chemother. 1977 Mar;11(3):388-91. doi: 10.1128/AAC.11.3.388. Antimicrob Agents Chemother. 1977. PMID: 140624 Free PMC article.
-
Hybridization analysis of three chloramphenicol resistance determinants from Clostridium perfringens and Clostridium difficile.Antimicrob Agents Chemother. 1989 Sep;33(9):1569-74. doi: 10.1128/AAC.33.9.1569. Antimicrob Agents Chemother. 1989. PMID: 2554801 Free PMC article.
-
Transformation of Heat-Treated Clostridium acetobutylicum Protoplasts with pUB110 Plasmid DNA.Appl Environ Microbiol. 1984 Oct;48(4):737-42. doi: 10.1128/aem.48.4.737-742.1984. Appl Environ Microbiol. 1984. PMID: 16346641 Free PMC article.
-
Molecular genetics and pathogenesis of Clostridium perfringens.Microbiol Rev. 1991 Dec;55(4):621-48. doi: 10.1128/mr.55.4.621-648.1991. Microbiol Rev. 1991. PMID: 1779929 Free PMC article. Review.
-
Cloning and hybridization analysis of ermP, a macrolide-lincosamide-streptogramin B resistance determinant from Clostridium perfringens.Antimicrob Agents Chemother. 1989 Aug;33(8):1346-53. doi: 10.1128/AAC.33.8.1346. Antimicrob Agents Chemother. 1989. PMID: 2552908 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Research Materials
Miscellaneous