Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Oct;77(10):1136-42.
doi: 10.1136/jnnp.2006.093146. Epub 2006 Jun 26.

Attentional deficits affect activities of daily living in dementia-associated with Parkinson's disease

K Bronnick  1 , U Ehrt, M Emre, P P De Deyn, K Wesnes, S Tekin, D Aarsland
Affiliations

Attentional deficits affect activities of daily living in dementia-associated with Parkinson's disease

K Bronnick et al. J Neurol Neurosurg Psychiatry. 2006 Oct.

Abstract

Objective: To investigate the effects of attentional deficits on activities of daily living (ADL) in patients with dementia associated with Parkinson's disease (PDD).

Method: 461 patients were assessed neuropsychologically. Factor analyses were used to differentiate attention from other cognitive functions and to differentiate different aspects of ADL functions. The effects of the attentional measure on ADL were examined using sequential multiple regression, controlling for age, sex, education, severity of motor symptoms and other cognitive functions.

Results: Three cognitive factors were identified, with one factor emerging as a measure of vigilance and focused attention. This factor predicted different aspects of ADL status even after controlling for motor functions and other cognitive factors. The attention factor was the single strongest cognitive predictor of ADL status, matching the strength of the effects of motor functions on ADL status.

Conclusion: Impaired attention is an important determinant of ADL functions in patients with PDD.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

References

    1. Aarsland D, Zaccai J C B. A systematic review of prevalence studies of dementia in Parkinson's disease. Mov Disord 2005201255–1263. - PubMed
    1. Aarsland D, Andersen K, Larsen J P.et al Prevalence and characteristics of dementia in Parkinson disease: an 8‐year prospective study. Arch Neurol 200360387–392. - PubMed
    1. Louis E D, Tang M X, Cote L.et al Progression of parkinsonian signs in Parkinson's disease. Arch Neurol 199956334–337. - PubMed
    1. Marras C, Rochon P, Lang A E. Predicting motor decline and disability in Parkinson's disease. Arch Neurol 2002591724–1728. - PubMed
    1. Schrag A, Jahanshahi M, Quinn N. What contributes to quality of life in patients with Parkinson's disease? J Neurol Neurosurg Psychiatry 200069308–312. - PMC - PubMed

Publication types