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. 2006 Oct;32(10):1523-8.
doi: 10.1007/s00134-006-0267-6. Epub 2006 Jun 28.

Automatic adjustment of pressure support by a computer-driven knowledge-based system during noninvasive ventilation: a feasibility study

Anne Battisti  1 , Jean Roeseler, Didier Tassaux, Philippe Jolliet
Affiliations

Automatic adjustment of pressure support by a computer-driven knowledge-based system during noninvasive ventilation: a feasibility study

Anne Battisti et al. Intensive Care Med. 2006 Oct.

Abstract

Objective: To evaluate the feasibility of using a knowledge-based system designed to automatically titrate pressure support (PS) to maintain the patient in a "respiratory comfort zone" during noninvasive ventilation (NIV) in patients with acute respiratory failure.

Design and setting: Prospective crossover interventional study in an intensive care unit of a university hospital.

Patients: Twenty patients.

Interventions: After initial NIV setting and startup in conventional PS by the chest physiotherapist NIV was continued for 45 min with the automated PS activated.

Measurements and results: During automated PS minute-volume was maintained constant while respiratory rate decreased significantly from its pre-NIV value (20+/-3 vs. 25+/-3 bpm). There was a trend towards a progressive lowering of dyspnea. In hypercapnic patients PaCO(2) decreased significantly from 61+/-9 to 51+/-2 mmHg, and pH increased significantly from 7.31+/-0.05 to 7.35+/-0.03. Automated PS was well tolerated. Two system malfunctions occurred prompting physiotherapist intervention.

Conclusions: The results of this feasibility study suggest that the system can be used during NIV in patients with acute respiratory failure. Further studies should now determine whether it can improve patient-ventilator interaction and reduce caregiver workload.

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References

    1. Chest. 2003 Aug;124(2):699-713 - PubMed
    1. Crit Care Med. 2002 Mar;30(3):555-62 - PubMed
    1. Qual Health Care. 1995 Jun;4(2):80-9 - PubMed
    1. Intensive Care Med. 1995 Nov;21(11):871-9 - PubMed
    1. Intensive Care Med. 2005 Oct;31(10):1446-50 - PubMed

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