Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2006 Jul;61(7):552-3.
doi: 10.1136/thx.2006.060293.

COX-2: a link between airway inflammation and disordered chloride secretion in cystic fibrosis?

Editorial

COX-2: a link between airway inflammation and disordered chloride secretion in cystic fibrosis?

A Clayton et al. Thorax. 2006 Jul.

Abstract

Possible role for COX‐2 in the pathophysiology of CF

PubMed Disclaimer

Conflict of interest statement

Competing interests: none declared.

Comment on

References

    1. Riordan J R, Rommens J M, Kerem B.et al Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 19892451066–1073. - PubMed
    1. Vankeerberghen A, Cuppens H, Cassiman J J. The cystic fibrosis transmembrane conductance regulator: an intriguing protein with pleiotropic functions. J Cyst Fibros 2002113–29. - PubMed
    1. Zabner J, Smith J J, Karp P H.et al Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell 19982397–403. - PubMed
    1. Widdicombe J H, Bastacky S J, Wu D X.et al Regulation of depth and composition of airway surface liquid. Eur Respir J 1997102892–2897. - PubMed
    1. Matsui H, Grubb B R, Tarran R.et al Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 1998951005–1015. - PubMed