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Review
. 2006 Jun;64(6):295-9.
doi: 10.1111/j.1753-4887.2006.tb00213.x.

How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol

George Wolf  1
Affiliations
Review

How an increased intake of alpha-tocopherol can suppress the bioavailability of gamma-tocopherol

George Wolf. Nutr Rev. 2006 Jun.

Abstract

alpha-Tocopherol is the only form of vitamin E in vitamin supplements, whereas gamma-tocopherol is the predominant form of vitamin E in the US diet. gamma-Tocopherol has beneficial properties as an anti-inflammatory and possibly anti-atherogenic and anticancer agent. Excess a-tocopherol taken in supplements causes a reduction of gamma-tocopherol concentration in plasma. The biochemical mechanism of this effect, which is important to human nutrition, has recently been elucidated.

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