Natural neo acids and neo alkanes: their analogs and derivatives
- PMID: 16808146
- DOI: 10.1007/s11745-006-5103-9
Natural neo acids and neo alkanes: their analogs and derivatives
Abstract
This review presents more than 260 naturally occurring (as well as 47 synthesized) neo fatty (carboxylic) acids, neo alkanes, and their analogs and derivatives, isolated and identified from plants, algae, fungi, marine invertebrates, and microorganisms, that demonstrate different biological activities. These natural metabolites are good prospects for future chemical preparations as antioxidants, and also as anticancer, antimicrobial, and antibacterial agents. Described also are some synthetic bioactive compounds containing a tertiary butyl group(s) that have shown high anticancer, antifungal, and other activities. Applications of some neo fatty (carboxylic) acid derivatives in cosmetic, agronomic, and pharmaceutical industries also are considered. This is the first review to consider naturally occurring neo fatty (carboxylic) acids, neo alkanes, and other metabolites containing a tertiary butyl group(s) [or tert-butyl unit(s)].
Similar articles
-
Bioactive acetylenic metabolites.Phytomedicine. 2013 Oct 15;20(13):1145-59. doi: 10.1016/j.phymed.2013.06.009. Epub 2013 Jul 16. Phytomedicine. 2013. PMID: 23871125 Review.
-
Abietane acids: sources, biological activities, and therapeutic uses.Planta Med. 1993 Dec;59(6):485-90. doi: 10.1055/s-2006-959744. Planta Med. 1993. PMID: 8302943 Review.
-
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities.Org Biomol Chem. 2015 Jul 14;13(26):7248-56. doi: 10.1039/c5ob00773a. Epub 2015 Jun 9. Org Biomol Chem. 2015. PMID: 26055397
-
Anticancer activity of natural and synthetic acetylenic lipids.Lipids. 2006 Oct;41(10):883-924. doi: 10.1007/s11745-006-5044-3. Lipids. 2006. PMID: 17180879 Review.
-
Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives.Eur J Med Chem. 2009 Nov;44(11):4726-33. doi: 10.1016/j.ejmech.2009.05.028. Epub 2009 Jun 6. Eur J Med Chem. 2009. PMID: 19560843
Cited by
-
Novel B(12)-dependent acyl-CoA mutases and their biotechnological potential.Biochemistry. 2012 Aug 7;51(31):6039-46. doi: 10.1021/bi300827v. Epub 2012 Jul 23. Biochemistry. 2012. PMID: 22803641 Free PMC article. Review.
-
Phenolic and flavonoid contents and antioxidant activity of an endophytic fungus Nigrospora sphaerica (EHL2), inhabiting the medicinal plant Euphorbia hirta (dudhi) L.Arch Microbiol. 2022 Jan 17;204(2):140. doi: 10.1007/s00203-021-02650-7. Arch Microbiol. 2022. PMID: 35039945 Free PMC article.
-
tert-Butylphenolic Derivatives from Paenibacillus odorifer-A Case of Bioconversion.Molecules. 2018 Aug 5;23(8):1951. doi: 10.3390/molecules23081951. Molecules. 2018. PMID: 30081602 Free PMC article.
-
Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice.Adv Pharm Bull. 2014 Oct;4(Suppl 1):429-36. doi: 10.5681/apb.2014.063. Epub 2014 Aug 25. Adv Pharm Bull. 2014. PMID: 25364658 Free PMC article.
-
In Silico Prediction of Steroids and Triterpenoids as Potential Regulators of Lipid Metabolism.Mar Drugs. 2021 Nov 22;19(11):650. doi: 10.3390/md19110650. Mar Drugs. 2021. PMID: 34822521 Free PMC article. Review.
