Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Nov;90(11):1398-403.
doi: 10.1136/bjo.2006.092973. Epub 2006 Jun 29.

Peripapillary fundus perimetry in eyes with glaucoma

Affiliations

Peripapillary fundus perimetry in eyes with glaucoma

E Convento et al. Br J Ophthalmol. 2006 Nov.

Abstract

Aims: To evaluate, with fundus perimetry, the peripapillary differential light threshold (DLT) in eyes with glaucoma and ocular hypertension (OHT), and compare it with peripapillary retinal nerve fibre layer (RNFL) thickness.

Methods: 35 glaucomatous, 29 OHT and 24 control eyes were included. Peripapillary DLT at 1 degrees from the optic nerve head was quantified with fundus perimetry; peripapillary RNFL thickness was measured over the same area by optical coherence tomography.

Results: Mean (SD) peripapillary DLT was 19.2 (1.7), 17.6 (4.2) and 10.1 (6.9) dB in control, OHT and glaucomatous eyes, respectively (p<0.001). Mean (SD) RNFL thickness was 98.4 (35.3), 83.9 (35.1) and 55.8 (28.2) microm, respectively (p<0.001). Mean peripapillary DLT showed higher sensitivity and specificity in differentiating the three groups compared with RNFL thickness.

Conclusion: Progressive, significant reduction of peripapillary DLT was documented in OHT and glaucomatous eyes compared with controls (p<0.001). DLT reduction parallels RNFL reduction.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None.

References

    1. Sommer A, Miller N R, Pollack I.et al The nerve fiber layer in the diagnosis of glaucoma. Arch Ophthalmol 1977952149–2156. - PubMed
    1. Quigley H A, Katz J, Derick R J.et al An evaluation of optic disc and nerve fiber layer examinations in monitoring progression of early glaucoma damage. Ophthalmology 19929919–28. - PubMed
    1. Quigley H A, Dunkelberger G R, Green W R. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol 1989107453–464. - PubMed
    1. Quigley H A, Addicks E M, Green W R. Optic nerve damage in human glaucoma. III: Quantitative correlation of nerve fiber loss and visual field defect in glaucoma, ischemic neuropathy, papilledema, and toxic neuropathy, Arch Ophthalmol 1982100135–146. - PubMed
    1. Mikelberg F S, Yidegiligne H M, Shulzer M. Optic nerve axon count and axon diameter in patients with ocular hypertension and normal visual fields. Ophthalmology 1995102342–348. - PubMed