Comment
doi: 10.1038/sj.ki.5000321.
ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7)
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- PMID: 16810285
- DOI: 10.1038/sj.ki.5000321
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Comment
ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7)
Kidney Int.
2006 Jul.
Free article
Abstract
The discovery of angiotensin-converting enzyme 2 (ACE-2) has revealed a far more complex enzymatic cascade that may influence the renin-angiotensin system within the kidney, specifically the expression of the functional products angiotensin II (Ang II) and Ang-(1-7). The regulation of this critical system involved in blood pressure control must now encompass the integral relationship of ACE and ACE-2 activities.
Comment on
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Developmental expression of ACE2 in the SHR kidney: a role in hypertension?Kidney Int. 2006 Jul;70(1):34-41. doi: 10.1038/sj.ki.5000428. Epub 2006 May 17. Kidney Int. 2006. PMID: 16710353
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