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Comment
. 2006 Jul;70(1):8-10.
doi: 10.1038/sj.ki.5000321.

ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7)

M C Chappel  1 , C M Ferrario
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Free article
Comment

ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7)

M C Chappel et al. Kidney Int. 2006 Jul.
Free article

Abstract

The discovery of angiotensin-converting enzyme 2 (ACE-2) has revealed a far more complex enzymatic cascade that may influence the renin-angiotensin system within the kidney, specifically the expression of the functional products angiotensin II (Ang II) and Ang-(1-7). The regulation of this critical system involved in blood pressure control must now encompass the integral relationship of ACE and ACE-2 activities.

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