Platelet aggregation: Part II Some results from a new method of study
- PMID: 16810986
- PMCID: PMC480433
- DOI: 10.1136/jcp.15.5.452
Platelet aggregation: Part II Some results from a new method of study
Abstract
The light transmitted through a suspension of platelets increases if the platelets aggregate. A method derived from this observation has been used to study the kinetics of platelet aggregation. Aggregation is more rapid at 37 degrees C., with rapid stirring, with high concentrations of adenosine diphosphate, and a high platelet concentration; a decrease in any of these conditions slows the process.
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References
-
- Nature. 1962 Jun 9;194:927-9 - PubMed
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